In the radiological examination of the spine one frequently sees in association with kyphoses very varied contours of the upper and lower vertebral margins. Mechanical Compression and Nucleus Pulposus Application on Dorsal Root the disc core is presumed to contribute to intervertebral disc hernia-related pain. This report examines 18 surgically proven L3/4 herniated nucleus pulposus ( HNP), all having myelogram, CT and adequate neurological evaluation. It will focus.

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Taken together, these results may therefore indicate that a single episode of NP leakage does not result in lasting changes in neuronal activity, but that any such effects are restricted to acute and short-lasting events. Lumbar disc herniation occurs 15 times more often than cervical neck disc herniation, and it is one of the most common causes of low back pain. Thus, a herniation of the L4—5 disc compresses the L5 nerve root.

A possible element in the pathogenesis of low-back pain”. Song Z, et al.

This study was supported by grants from the Dr. Please review our privacy policy. The review of Rasoul MR et al. Articles Cases Courses Quiz. Compression of the cauda equina can cause permanent nerve damage or nuklleus which can result in loss of bowel and bladder control and sexual dysfunction. Roxanne Mae Birador SN; 2. Check for errors and try again.

All experimental procedures were approved by the regional animal ethics committee. The uernia of afferent pathways on the thalamus of the rat.

Lateral L3/4 herniated nucleus pulposus: clinical and imaging considerations.

Severe herniations may pulpous heal of their own accord and may require surgery. Back exercises include the prone press-ups, upper back extension, transverse abdominis bracing, and floor bridges. A Schematic drawing with a sciatic nerve and stimulation electrode; b dorsal root ganglion DRG for exposure to nucleus pulposus NP and light mechanical compression; c recording electrode at the surface of the spinal cord; d recording site in the ventral posterior lateral VPL nucleus.


The condition may be referred to as a slipped discbut this term is not accurate as the spinal discs are firmly attached between the vertebrae and cannot “slip” out of place.

Herniq electrode track and recording site corresponding to d in the schematic drawing in A is indicated by a dotted vertical line and a filled circle.

Organization of the spinocervicothalamic pathway in the rat. Because there are various causes of back injuries, prevention must be comprehensive.

A craniotomy herhia performed, and the dura mater was removed to insert a recording electrode into the VPL nucleus of the thalamus Fig. The thalamus is the major brain relay nucleus for sensory information, including transmission in nociceptive pathways from the spinal cord en route to cortical regions where the information is processed further.

Tears are almost nukkeus postero-lateral on the back of the sides owing to the presence of the posterior longitudinal ligament in the spinal canal. The mean number of evoked responses is presented as a percentage of baseline records.

From Occiput to Coccyx”. Most disc herniations occur when a person is in their thirties or forties when the nucleus pulposus is still a gelatin-like substance.

A possible element in the pathogenesis of nukleuz pain. Thalamic activation in a disc herniation model. The following pulposud can be used as a protocol for rehabilitation following a lumbar microdiscectomy [72]: Effect of nucleus pulposus on the neural activity of dorsal root ganglion.

Xu Q, et al. Analysis Original data records from the electrophysiological experiments were stored online using a software system designed by E.

Other preventative measures are to lose weight and not to work oneself past fatigue. Light mechanical compression was induced by gently dislocating the L4 DRG with a G needle and was maintained by inserting the needle in the underlying bone, as previously described by Omarker and Myers.


A spino-reticulo-thalamic pathway in the rat: Herniations usually occur postero-laterally, at the points where the anulus fibrosus is relatively thin and is not reinforced by the posterior or anterior longitudinal ligament. The jelly-like contents of the disc then move into the spinal canal, pressing against the spinal nerves, which may produce intense and potentially disabling pain and other symptoms.

Aoki Y, et al. The effects of compression upon conduction in myelinated axons of the isolated frog sciatic nerve. Br J Gen Pract. Some authors favour degeneration of the intervertebral disc as the major cause of spinal disc herniation and cite trauma as a minor cause. Most minor herniations heal within several weeks. During an evaluation, tests may be performed to confirm or rule out other possible causes with similar symptoms — spondylolisthesis, degeneration, tumorsmetastases and space-occupying lesionsfor instance — as well as to evaluate the efficacy of potential treatment options.

MRI scan of large herniation on the right of the disc between L4 and L5 vertebrae.

Lateral L3/4 herniated nucleus pulposus: clinical and imaging considerations.

Example of a herniated disc at L5—S1 in the lumbar spine. It may result in back pain, pu,posus or sensation in different parts of the body, and physical disability. Am J Phys Med Rehabil. Surgery may be useful when a herniated disc is causing significant pain radiating into the leg, significant leg weakness, bladder problems, or loss of bowel control. At this stage, no remnants pullosus the previously applied NP were visible on macroscopic inspection.

Inflammatory cytokines in the herniated disc of the lumbar spine.